作者Pan, Haitao,
作者SpringerLink (Online service)
書名Bayesian adaptive design for immunotherapy and targeted therapy / by Haitao Pan, Ying Yuan
出版項Singapore : Springer Nature Singapore : Imprint: Springer, 2023
其他作者Yuan, Ying,
說明1 online resource (xi, 262 pages) : illustrations (some color), digital ; 24 cm
文字text
無媒介computer
成冊online resource
說明text file PDF
附註Introduction to Adaptive Design and Delayed Outcomes -- Basics of Bayesian Statistics -- Phase I Dose-finding Design -- Phase II Design for Interim Monitoring -- Phase I-II Dose-finding Design -- Drug Combination Trial Design -- Conclusion
This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice
主題Immunotherapy -- Statistical methods
Drug targeting -- Statistical methods
Clinical trials -- Design -- Statistical methods
Bayesian statistical decision theory
Biostatistics
ISBN/ISSN9789811981760 (electronic bk.)
9789811981746 (paper)
10.1007/978-981-19-8176-0
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