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其他作者 | Yuan, Ying, |
說明 | 1 online resource (xi, 262 pages) : illustrations (some color), digital ; 24 cm |
文字 | text |
無媒介 | computer |
成冊 | online resource |
說明 | text file PDF |
附註 | Introduction to Adaptive Design and Delayed Outcomes -- Basics of Bayesian Statistics -- Phase I Dose-finding Design -- Phase II Design for Interim Monitoring -- Phase I-II Dose-finding Design -- Drug Combination Trial Design -- Conclusion |
| This book provides a comprehensive review of novel adaptive trial designs for targeted therapies and immunotherapies. This book covers a wide range of novel statistical designs for various clinical settings, including early phase dose-escalation study, proof-of-concept trials, and confirmatory studies with registrational. The book includes real-life examples and software to facilitate practitioners to learn and use the designs in practice |
主題 | Immunotherapy -- Statistical methods |
| Drug targeting -- Statistical methods |
| Clinical trials -- Design -- Statistical methods |
| Bayesian statistical decision theory |
| Biostatistics |
ISBN/ISSN | 9789811981760 (electronic bk.) |
| 9789811981746 (paper) |
| 10.1007/978-981-19-8176-0 |