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001 AAI13878919
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008 190624s2019 xx sbm 000 0 eng d
020 9781392149942
035 (MiAaPQ)AAI13878919
035 (MiAaPQ)sunyalb:12614
040 MiAaPQ|beng|cMiAaPQ|dNTU
100 1 Brunelle, Erica
245 10 Evaluation of Fingerprint Content for Forensic Crime Scene
Analysis and Drug Metabolite Detection
264 0 |c2019
300 1 online resource (152 pages)
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
500 Source: Dissertation Abstracts International, Volume: 80-
09(E), Section: B
500 Adviser: Jan Halamek
502 Thesis (Ph.D.)--State University of New York at Albany,
2019
504 Includes bibliographical references
520 With respect to criminal investigations, one key piece of
evidence that often gets overlooked are fingerprints. For
years, fingerprint samples have been believed to be useful
only for matching purposes using their unique ridges,
shapes, and sizes. With the rapid growth of forensic
science, it has become evident that the development of
fingerprint analysis has been stagnant. The traditional
approach has been advantageous for the identification of
many individuals; however, many fingerprint samples have
been labeled "unusable" due to smudging, smearing, or any
one of a myriad of reasons that could cause inconclusive
matches. These samples can, however, still be of value
using a newly established method for the analysis of the
fingerprint content itself
520 Because fingerprints are such a small biological sample
compared to blood, semen or other body fluids, little to
no DNA can be obtained from them. Additionally, they are
very rarely whole or in pristine condition. However, with
these methods they can only identify an individual if the
image can be seen, if DNA is found, and/or only if there
is a matching image or DNA profile already in the system.
In such cases where images cannot be made or matches are
not found, it would be beneficial for law enforcement to
have information about their suspects, even if it is not
the exact identification
520 The ultimate goal of the first half of the research
described here was to identify originator attributes---
specifically sex---using chemical analysis methods.
Additionally, the time since deposition of the fingerprint
in conjunction with sex identification was investigated.
The systems presented here are designed to be versatile
and adjustable in order to produce easily interpretable
results, making it possible for all members of law
enforcement to use and understand the results regardless
of the level of scientific knowledge or specialized
training. One day, the goal would be to have these systems
adapted to a field-deployable system so that the analyses
can be performed directly on-site. However, the
development of such a system is beyond the scope of the
research presented here
520 The second half of the research described here focuses on
drug metabolite detection. The sudden increase in states
legalizing marijuana has forced law enforcement into a
situation where the use/consumption is legal, but there
are no limitations for what is acceptable for driving or
operating machinery. As a result, there is still a zero-
tolerance policy when it comes to driving and operating
machinery---unlike alcohol which has very clear legal
limits. Marijuana---which contains Delta9-
Tetrahydrocannabinol (Delta9-THC) as its active compound--
-is a drug that is used mainly for its psychoactive
properties. When looking to get high, people take this
drug by smoking or ingesting it. Medicinally, it can
relieve pain for those with chronic illnesses or
disorders. In many states, marijuana is illegal for
recreational use and is tightly monitored for medicinal
use. When it comes to alcohol use, law enforcement have
clear guidelines and the breathalyzer as their means of
detecting the amount of alcohol in a person's system as
determining their ability to drive. Currently, there is no
such device for marijuana use nor are there any quantity
guidelines
520 When marijuana is used, the active compound Delta9-THC is
converted to several metabolites such as 11-Nor-9-carboxy-
THC (THC-COOH). As a metabolite, this compound is
reportedly released by the body via blood, sweat or urine.
However, based on the experience garnered from literature
and previous research, it was anticipated that THC-COOH
would mirror other metabolites and be found in the sweat
secretions of fingerprints. As such, the focus of this
research was to develop and optimize a novel, non-invasive
approach to THC-COOH detection using a person's
fingerprints. Ultimately competitive enzyme-linked
immunosorbent assay (ELISA) was used to detect the THC-
COOH in the fingerprint sample. Ideally, law enforcement
would be able to use this on the roadside in a similar
manner to how the sex identification methods could be
applied on-site at crime scenes. The methodology used for
this research is straightforward and can easily be
modified for additional illicit drugs and their
metabolites
533 Electronic reproduction.|bAnn Arbor, Mich. :|cProQuest,
|d2019
538 Mode of access: World Wide Web
650 4 Analytical chemistry
650 4 Biochemistry
650 4 Chemistry
655 7 Electronic books.|2local
690 0486
690 0487
690 0485
710 2 ProQuest Information and Learning Co
710 2 State University of New York at Albany.|bChemistry
773 0 |tDissertation Abstracts International|g80-09B(E)
856 40 |uhttps://pqdd.sinica.edu.tw/twdaoapp/servlet/
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