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001 978-981-19-8176-0
003 DE-He213
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006 m o d
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008 230419s2023 si s 0 eng d
020 9789811981760|q(electronic bk.)
020 9789811981746|q(paper)
024 7 10.1007/978-981-19-8176-0|2doi
040 GP|cGP|erda
041 0 eng
050 4 RM276
072 7 PBT|2bicssc
072 7 MED090000|2bisacsh
072 7 PBT|2thema
082 04 615.370151|223
100 1 Pan, Haitao,|eauthor
245 10 Bayesian adaptive design for immunotherapy and targeted
therapy /|cby Haitao Pan, Ying Yuan
264 1 Singapore :|bSpringer Nature Singapore :|bImprint:
Springer,|c2023
300 1 online resource (xi, 262 pages) :|billustrations (some
color), digital ;|c24 cm
336 text|btxt|2rdacontent
337 computer|bc|2rdamedia
338 online resource|bcr|2rdacarrier
347 text file|bPDF|2rda
505 0 Introduction to Adaptive Design and Delayed Outcomes --
Basics of Bayesian Statistics -- Phase I Dose-finding
Design -- Phase II Design for Interim Monitoring -- Phase
I-II Dose-finding Design -- Drug Combination Trial Design
-- Conclusion
520 This book provides a comprehensive review of novel
adaptive trial designs for targeted therapies and
immunotherapies. This book covers a wide range of novel
statistical designs for various clinical settings,
including early phase dose-escalation study, proof-of-
concept trials, and confirmatory studies with
registrational. The book includes real-life examples and
software to facilitate practitioners to learn and use the
designs in practice
650 0 Immunotherapy|xStatistical methods
650 0 Drug targeting|xStatistical methods
650 0 Clinical trials|xDesign|xStatistical methods
650 0 Bayesian statistical decision theory
650 14 Biostatistics
700 1 Yuan, Ying,|eauthor
710 2 SpringerLink (Online service)
773 0 |tSpringer Nature eBook
856 40 |uhttps://doi.org/10.1007/978-981-19-8176-0
912 Springer |b111206084615
