MARC 主機 00000cam  2200000Ia 4500 
001    ocn162569262 
003    OCoLC 
005    20110614113907.0 
006    m        d         
007    cr cn||||||||| 
008    070806s2000    caua    sb    001 0 eng d 
020    9780120777006 
020    0120777002 
035    (OCoLC)162569262 
037    89027:89027|bElsevier Science & Technology|nhttp://
       www.sciencedirect.com 
040    OPELS|beng|cOPELS|dOCLCQ 
050 14 QP624.5.S78|bB36 2000eb 
060 14 2000 F-375 
060 14 QU 58.5|bB212f 2000 
082 04 572.8/633|222 
100 1  Banaszak, Leonard 
245 10 Foundations of structural biology|h[electronic resource] /
       |cLeonard J. Banaszak 
260    San Diego, Calif. :|bAcademic,|cc2000 
300    xi, 168 p. :|bill. ;|c28 cm 
504    Includes bibliographical references and index 
505 0  Introduction to Protein Structure. -- Solid State and 
       Solution Methods for Determining Biological Macromolecular
       Structure. -- Crystallographic Coordinates and 
       Stereodrawings. -- Properties of Biomacromolecules in the 
       Crystalline State. -- Quaternary Structure of Proteins. --
       Secondary Structure of Proteins. -- Domains and Super-
       secondary Structure. -- Conformational States in Crystal 
       and NMR Structures. -- Hydrogen Bonds and Water Molecules 
       in Crystalline Proteins. -- Protein and Nucleic Acid 
       Complexes. -- Metal Ions Bound to Proteins. -- Lipid 
       Protein Interactions 
520    Imagine trying to understand an engine without visualizing
       its moving parts. Biological processes involve far more 
       complex chemical reactions and components than any engine.
       Furthermore, the parts work together to do many more 
       functions than an engine which sole task is to turn a 
       shaft. Understanding the implications of the three-
       dimensional coordinates for a molecule with several 
       thousand atoms requires an understanding of, and practice 
       with, 3D imaging. For many biologists, this means 
       acquiring a whole new set of skills. Foundations of 
       Structural Biology is aimed at helping the reader develop 
       visualization skills for protein or DNA segments, while 
       also describing the fundamental principles underlying the 
       organization and interaction between these complex 
       molecules. Key Features * Explains how to use coordinate 
       databases and atomic coordinates of biological 
       macromolecules * Teaches the skills of stereoviewing * 
       Contains computer-generated stereographics * Describes the
       principles of symmetry and handedness in proteins and DNA 
       * Introduces metal and lipid binding proteins and DNA-
       protein interactions * Explains the principles involved in
       understanding secondary and quaternary structure * 
       Includes coverage of protein-metal, protein-nucleic acid, 
       and protein-lipid interactions 
533    Electronic reproduction.|bAmsterdam :|cElsevier Science & 
       Technology,|d2007.|nMode of access: World Wide Web.
       |nSystem requirements: Web browser.|nTitle from title 
       screen (viewed on Aug. 2, 2007).|nAccess may be restricted
       to users at subscribing institutions 
650  0 DNA|xStructure 
650  0 Proteins|xStructure 
650  0 DNA-binding protein interactions 
650  0 Three-dimensional imaging in biology 
650  4 DNA-protein interactions 
650 12 DNA|xchemistry 
650 17 Macromoleculen.|2gtt 
650 17 Ruimtelijke structuur.|2gtt 
650 17 Kristallografie.|2gtt 
650 17 Chemische structuur.|2gtt 
650 22 DNA-Binding Proteins|xmetabolism 
650 22 Proteins|xchemistry 
650 22 Structure-Activity Relationship 
655  4 Electronic books 
710 2  ScienceDirect (Online service) 
776 1  |cOriginal|z0120777002|z9780120777006|w(DLC)   99063001
       |w(OCoLC)42622244 
856 40 |3ScienceDirect|uhttp://www.sciencedirect.com/science/book
       /9780120777006 
912    Elsevier 
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