MARC 主機 00000cam 2200000Ia 4500 001 ocn162569262 003 OCoLC 005 20110614113907.0 006 m d 007 cr cn||||||||| 008 070806s2000 caua sb 001 0 eng d 020 9780120777006 020 0120777002 035 (OCoLC)162569262 037 89027:89027|bElsevier Science & Technology|nhttp:// www.sciencedirect.com 040 OPELS|beng|cOPELS|dOCLCQ 050 14 QP624.5.S78|bB36 2000eb 060 14 2000 F-375 060 14 QU 58.5|bB212f 2000 082 04 572.8/633|222 100 1 Banaszak, Leonard 245 10 Foundations of structural biology|h[electronic resource] / |cLeonard J. Banaszak 260 San Diego, Calif. :|bAcademic,|cc2000 300 xi, 168 p. :|bill. ;|c28 cm 504 Includes bibliographical references and index 505 0 Introduction to Protein Structure. -- Solid State and Solution Methods for Determining Biological Macromolecular Structure. -- Crystallographic Coordinates and Stereodrawings. -- Properties of Biomacromolecules in the Crystalline State. -- Quaternary Structure of Proteins. -- Secondary Structure of Proteins. -- Domains and Super- secondary Structure. -- Conformational States in Crystal and NMR Structures. -- Hydrogen Bonds and Water Molecules in Crystalline Proteins. -- Protein and Nucleic Acid Complexes. -- Metal Ions Bound to Proteins. -- Lipid Protein Interactions 520 Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft. Understanding the implications of the three- dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging. For many biologists, this means acquiring a whole new set of skills. Foundations of Structural Biology is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules. Key Features * Explains how to use coordinate databases and atomic coordinates of biological macromolecules * Teaches the skills of stereoviewing * Contains computer-generated stereographics * Describes the principles of symmetry and handedness in proteins and DNA * Introduces metal and lipid binding proteins and DNA- protein interactions * Explains the principles involved in understanding secondary and quaternary structure * Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions 533 Electronic reproduction.|bAmsterdam :|cElsevier Science & Technology,|d2007.|nMode of access: World Wide Web. |nSystem requirements: Web browser.|nTitle from title screen (viewed on Aug. 2, 2007).|nAccess may be restricted to users at subscribing institutions 650 0 DNA|xStructure 650 0 Proteins|xStructure 650 0 DNA-binding protein interactions 650 0 Three-dimensional imaging in biology 650 4 DNA-protein interactions 650 12 DNA|xchemistry 650 17 Macromoleculen.|2gtt 650 17 Ruimtelijke structuur.|2gtt 650 17 Kristallografie.|2gtt 650 17 Chemische structuur.|2gtt 650 22 DNA-Binding Proteins|xmetabolism 650 22 Proteins|xchemistry 650 22 Structure-Activity Relationship 655 4 Electronic books 710 2 ScienceDirect (Online service) 776 1 |cOriginal|z0120777002|z9780120777006|w(DLC) 99063001 |w(OCoLC)42622244 856 40 |3ScienceDirect|uhttp://www.sciencedirect.com/science/book /9780120777006 912 Elsevier
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